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There are several matches for 'histone deacetylase family protein'.
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660 matches
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organism
protein
1)
Homo sapiens
CHD4 - Chromodomain-helicase-DNA-binding
protein
4; Component of the
histone
deacetylase
NuRD complex which participates in the remodeling of chromatin by deacetylating
histones
. Belongs to the SNF2/RAD54 helicase
family
.
[a.k.a. NP_001264.2, 2EE1, XM_006718958.1]
2)
Homo sapiens
ANKRA2 - Ankyrin repeat
family
A
protein
2; May regulate the interaction between the 3M complex and the
histone
deacetylases
HDAC4 and HDAC5. May also regulate LRP2/megalin (By similarity).
[a.k.a. XM_005248560, 3V31, NP_075526]
3)
Homo sapiens
JDP2 - Jun dimerization
protein
2; Component of the AP-1 transcription factor that represses transactivation mediated by the Jun
family
of
proteins
. Involved in a variety of transcriptional responses associated with AP-1 such as UV- induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting
histone
deacetylase
3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of
histones
and the assembly of chromatin.
[a.k.a. UPI000006F3AE, XP_005267389.1, ENST00000437176.5]
4)
Homo sapiens
ZNF431 - Zinc finger
protein
431; Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2
histone
deacetylases
. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5'-GCGCCC-3' in the promoter of PTCH1 (By similarity). Belongs to the krueppel C2H2-type zinc-finger
protein
family
.
[a.k.a. ENSP00000470668, Q8TF32, KIAA1969]
5)
Homo sapiens
MYBBP1A - Myb-binding
protein
1A; May activate or repress transcription via interactions with sequence specific DNA-binding
proteins
(By similarity). Repression may be mediated at least in part by
histone
deacetylase
activity (HDAC activity) (By similarity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated
histone
H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity). Has a role in rRNA biogenesis together with PWP1. Belongs to the MYBBP1A
family
.
[a.k.a. Q9UF99, ENST00000570986, NP_055335]
6)
Homo sapiens
ZNF703 - Zinc finger
protein
703; Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of
histone
deacetylases
to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development; Belongs to the Elbow/Noc
family
.
[a.k.a. NM_025069, ZEPPO1, ENSG00000183779]
7)
Mus musculus
Tgif2 - Homeobox
protein
TGIF2; Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD
proteins
. Probably represses transcription via the recruitment of
histone
deacetylase
proteins
(By similarity); Belongs to the TALE/TGIF homeobox
family
.
[a.k.a. TGF-beta-induced transcription factor 2, ENSMUSP00000073074, 5730599O09Rik]
8)
Mus musculus
Brms1l - Breast cancer metastasis-suppressor 1-like
protein
; Involved in the
histone
deacetylase
(HDAC1)-dependent transcriptional repression activity. When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth (By similarity); Belongs to the BRMS1
family
.
[a.k.a. NM_001037756, ENSMUST00000219419, Brms1l-202]
9)
Mus musculus
Zfp467 - Zinc finger
protein
467; Transcription factor that promotes adipocyte differentiation and suppresses osteoblast differentiation in the bone marrow. Enhances the osteoclast-supporting ability of stromal cells. Binds with STAT3 the consensus sequence 5'-CTTCTGGGAAGA-3' of the acute phase response element (APRE). Transactivates several promoters including FOS, OSM and PPARG. Recruits a
histone
deacetylase
complex. Belongs to the krueppel C2H2-type zinc-finger
protein
family
.
[a.k.a. BAC28171.1, NP_065614.2, XM_006506544.1]
10)
Mus musculus
Ankra2 - Ankyrin repeat
family
A
protein
2; May regulate the interaction between the 3M complex and the
histone
deacetylases
HDAC4 and HDAC5 (By similarity). May also regulate LRP2/megalin.
[a.k.a. ENSMUSP00000093184, NM_001271392, UPI000052CAD1]
11)
Mus musculus
Jdp2 - Jun dimerization
protein
2; Component of the AP-1 transcription factor that represses transactivation mediated by the Jun
family
of
proteins
. Involved in a variety of transcriptional responses associated with AP-1, such as UV- induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting
histone
deacetylase
3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of
histones
and the assembly of chromatin (By similarity); Belongs to the bZIP
family
. ATF subfamily.
[a.k.a. ENSMUSP00000129985, Jdp2-204, ENSMUST00000171754.2]
12)
Mus musculus
Mybbp1a - Myb-binding
protein
1A; May activate or repress transcription via interactions with sequence specific DNA-binding
proteins
. Repression may be mediated at least in part by
histone
deacetylase
activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated
histone
H3 'Lys-9' (H3K9me2) on the PER2 promoter. Has a role in rRNA biogenesis together with PWP1 (By similarity). Belongs to the MYBBP1A
family
.
[a.k.a. Mybbp1a-207, R-MMU-5250924, ENSMUST00000134119.1]
13)
Mus musculus
Aatf -
Protein
AATF; May function as a general inhibitor of the
histone
deacetylase
HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression (By similarity). Belongs to the AATF
family
.
[a.k.a. XM_006533789, XP_006533852.1, CCDS25186.1]
14)
Caenorhabditis elegans
rba-1 - Probable
histone
-binding
protein
rba-1; Core
histone
-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and
histone
deacetylases
to their
histone
substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger
protein
ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1
family
.
[a.k.a. K07A1.11, CAB03172, WBGene00004312]
15)
Caenorhabditis elegans
C16C10.4 - Probable
histone
deacetylase
complex subunit SAP18; Acts in transcription repression. Involved in the tethering of the SIN3 complex to core
histone
proteins
(By similarity). Belongs to the SAP18
family
.
[a.k.a. NM_065432.4, Q09250, CE01495]
16)
Saccharomyces cerevisiae
HST2 - Cytoplasmic NAD(+)-dependent
protein
deacetylase
; deacetylation targets are primarily cytoplasmic
proteins
; member of the silencing information regulator 2 (Sir2)
family
of NAD(+)-dependent
protein
deacetylases
; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent
histone
deacetylase
activity in vitro; contains a nuclear export signal (NES); function regulated by its nuclear export; Belongs to the sirtuin
family
. Class I subfamily.
[a.k.a. YPL015C, NM_001183829, 1Q17]
17)
Saccharomyces cerevisiae
RXT3 - Transcriptional regulatory
protein
RXT3; Component of the Rpd3L
histone
deacetylase
complex; involved in
histone
deacetylation;
protein
abundance increases in response to DNA replication stress; Belongs to the RXT3
family
.
[a.k.a. YDL076C, NP_010207, DAA11783.1]
18)
Saccharomyces cerevisiae
HST3 - NAD-dependent
histone
deacetylase
HST3; Member of the Sir2
family
of NAD(+)-dependent
protein
deacetylases
; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism.
[a.k.a. YOR025W, P53687, 854190]
19)
Saccharomyces cerevisiae
HST4 - NAD-dependent
histone
deacetylase
HST4; NAD(+)-dependent
protein
deacetylase
; deacetylation targets are primarily mitochondrial
proteins
; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism; accumulates in mitochondria in response to biotin starvation and may link biotin metabolism with energy homeostasis; member of the Sir2
family
and may be the functional equivalent of human SIRT3.
[a.k.a. YDR191W, L000003043, 851772]
20)
Saccharomyces cerevisiae
SIR2 - Conserved NAD+ dependent
histone
deacetylase
of the Sirtuin
family
; deacetylation targets are primarily nuclear
proteins
; required for telomere hypercluster formation in quiescent yeast cells; involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and rDNA; negatively regulates initiation of DNA replication; functions as regulator of autophagy like mammalian homolog SIRT1, and also of mitophagy.
[a.k.a. YDL042C, S000002200, D6VRV4]
660 matches
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